In Vitro Anti-Cancer Properties of VERNOLAC: A University of Colombo Innovation

In Vitro Anti-Cancer Properties of VERNOLAC: A University of Colombo Innovation


At Fadna, we blend Ayurveda with modern science to create trusted wellness solutions. One of the most innovative outcomes of this approach is VERNOLAC — a scientifically developed polyherbal nutraceutical from the University of Colombo. Recent laboratory studies explored its effects on cancer stem-like cells, providing strong scientific validation for this herbal supplement.

Research Publication & LinkThe full research paper is published as a preprint on bioRxiv. You can read the detailed study here.
(This link directs to the original lab report, giving your readers access to the full methodology, data, and supplementary material.)


Research Overview


Researchers evaluated the in vitro anti-cancer properties of VERNOLAC using the NTERA-2 cl.D1 cell line. The supercritical CO₂ extract of VERNOLAC was tested through:

  • Sulforhodamine B cytotoxicity assay

  • Apoptosis detection (AO/EB staining, caspase 3/7 activity)

  • Scratch assay for cell migration

  • RT-PCR for TP53, Survivin, and mTOR expression

  • Free-radical scavenging & ROS assays


Key Findings

  • Significant anti-proliferative effect on cancer stem-like cells (IC50 = 41.12 µg/mL).

  • Minimal effect on non-cancerous cells (IC50 > 1000 µg/mL).

  • Induced early apoptosis and activated tumor suppressor TP53.

  • Reduced cell migration potential.

  • Increased ROS activity.

These findings suggest that VERNOLAC demonstrates promising laboratory-based activity, making it a valuable herbal nutraceutical for further research.


About VERNOLAC


Beyond research, VERNOLAC is available as a scientifically developed Ayurvedic nutraceutical designed to support overall well-being.

Ingredients:

  • Vernonia zeylanica

  • Nigella sativa

  • Leucas zeylanica

  • Hemidesmus indicus

  • Gynura pseudochina

When to Use: Half an hour before breakfast and dinner.
For Whom: Suitable for those seeking herbal wellness support (not recommended for children, pregnant or lactating mothers).


    Why Choose VERNOLAC?

  • Developed by the University of Colombo with advanced extraction methods.

  • Ayurveda-registered and scientifically evaluated.

  • Complements conventional care by supporting natural well-being.


Conclusion
The research on VERNOLAC highlights the value of combining traditional Ayurveda with scientific validation. As a result, VERNOLAC stands out as a trusted herbal nutraceutical with great potential for the future of holistic wellness.

What is Vernolac ?

Vernolac is a natural nutraceutical developed by the University of Colombo to support cancer management. It combines five key herbal ingredients, with Vernonia zeylanica as the main component, known for its anti-cancer, antioxidant, and cell-protective properties.

It helps inhibit abnormal cell growth, enhances overall wellness, and reduces discomforts linked to chemotherapy. Vernolac is designed to complement conventional cancer treatments, not replace them.

Dosage: Two capsules daily, taken half an hour before breakfast and dinner.

It is registered under the Department of Ayurveda and offers a natural, science-backed approach to improving quality of life during cancer care.

Vernolac

Rs.8400.00
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